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Common name: Diflubenzuron
IUPAC name: 1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl)urea
Chemical Abstracts name:N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide
CAS RN: [35367-38-5]
Mol. wt.: 310.7
Form:Colourless crystals; (tech., off-white to yellow crystals).
M.p.: 228 °C; (tech., 210-230 ºC, decomp.)
V.p.: 1.2×10-4 mPa (25 ºC) (gas saturation method)
Kow logP = 3.89
S.g./density: 1.56
Solubility In water 0.08 mg/l (pH 7, 25 ºC). In n-hexane 0.063, toluene 0.29, dichloromethane 1.8, methanol 1.1 (all in g/l, 20 °C).
Stability  Light-sensitive when in solution, but stable to sunlight as a solid. <0.5% decomposition after 1 d storage at 100 ºC; <0.5% after 7 d at 50 ºC. In aqueous solution (20 ºC), stable at pH 5 and 7 (DT50 >150 d), at pH 9 DT50 42 d. 
Oral Acute oral  LD50 for rats and mice >4640 mg/kg.
Skin and eye Acute percutaneous  LD50 for rabbits >2000, rats >10 000 mg/kg. Not a skin irritant; slight eye irritant (rabbits). Not a skin sensitiser (guinea-pigs).
Inhalation  LC50 for rats >2.88 mg/l.
NOEL (2 y) for rats 40 mg/kg diet. No teratogenic, mutagenic, or oncogenic effect was observed.
ADI (JMPR) 0.02 mg/kg b.w.
Toxicity class WHO (a.i.) III
EPA (formulation) III
Birds Acute oral  Dietary LC50 (8 d) for bobwhite quail and mallard ducks >4640 mg/kg diet.
Fish  LC50 (96 h) for zebra fish (Brachydanio rerio) >0.2, rainbow trout >0.2 mg/l.
Daphnia  LC50 (48 h) 7.1 mg/l.
Algae  LC50 for Selenastrum capricornutum >0.3 mg/l.
Other aquatic spp. LC50 for molluscs >200 mg/l.
Bees  Not hazardous to bees and predatory insects; LD50 (oral and contact) >100 mg/bee.
Worms   NOEC for Eisenia foetida 780 mg/kg substrate.

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