Common name: Chlorimuron-ethyl
IUPAC name: ethyl 2-(4-chloro-6-methoxypyrimidin-2-ylcarbamoylsulfamoyl)benzoate
Chemical Abstracts name:
ethyl 2-[[[[(4-chloro-6-methoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoate
CAS RN: [90982-32-4]
PHYSICAL CHEMISTRY
Mol. wt.: 414.8
Form: Colourless crystals.
M.p.: 181 ºC
V.p.: 4.9×10-7 mPa
KOW logP＝0.11 (pH 7)
Henry: 1.7×10-10 Pa m3 mol-1
S.g./density: 1.51 (25 ºC)
Solubility In water 9 (pH 5), 1200 (pH 7) (both in mg/l, 25 ºC). Low solubility in organic solvents.
Stability In water DT50 17-25 d (pH 5, 25 ºC).
TOXICOLOGY
Oral Acute oral LD50 for rats 4102 mg/kg.
Skin and eye Acute percutaneo LD50 for rabbits >2000 mg/kg. Not a skin irritant or eye irritant (rabbits). Not a skin sensitiser (guinea pigs).
Inhalation LC50 (4 h) for rats >5 mg/l air.
NOEL (2 y) for rats 250 mg/kg diet (12.5 mg/kg daily); (1 y) for dogs 250 mg/kg diet (6.25 mg/kg daily). NOEL in: reproduction (2-generation) in rats 250 mg/kg diet; teratogenicity in rats 30, rabbits 15 mg/kg.
ADI (JMPR) 0.020 mg/kg b.w.
Toxicity class WHO (a.i.) III
EPA (formulation) III
ECOTOXICOLOGY
Birds Acute oral LD50 (14 d) for mallard ducks >2510 mg/kg. Dietary LC50 for mallard ducks and bobwhite quail >5620 ppm.
Fish LC50 (96 h) for trout >1000, bluegill sunfish >100 mg/l.
Daphnia LC50 (48 h) 1000 mg/l.
Other aquatic spp. For Lemna gibba, EbC50 0.45 ppb, ErC50 45 mg/l, EC50 (frond counts) 0.27 ppb. LC50 for crayfish >1000 ppm.
Bees LD50 (48 h) >12.5 mg/bee.
Worms LC50 for earthworms (Eisenia foetida) >4050 mg/kg.
